What is 2′-Fucosyllactose?

What is 2′-Fucosyllactose?

2025-02-13

2′-Fucosyllactose (2′-FL) is a human milk oligosaccharide (HMO), a unique type of carbohydrate naturally found in human breast milk. As one of the most abundant HMOs, 2′-FL plays a crucial role in infant nutrition, gut health, and immune development.

 Effects of 2'-Fucosyllactose in Breast Milk

Biological Functions

 

1. Gut Microbiota Modulation

2′-FL serves as a prebiotic, selectively promoting the growth of beneficial bacteria such as Bifidobacterium species. These probiotics contribute to a balanced gut microbiome, which is essential for digestion and overall health.

 

2. Immune System Support

Research suggests that 2′-FL enhances immune function by preventing pathogenic bacteria from adhering to intestinal epithelial cells. By mimicking glycan structures found on the gut lining, 2′-FL acts as a decoy receptor, reducing the risk of infections.

 

3. Cognitive Development

Emerging studies indicate that HMOs, including 2′-FL, may support brain development and cognitive function. They influence neural growth by modulating gut-brain interactions and promoting the production of beneficial metabolites.

 

Applications in Infant Formula and Beyond

 

Due to its proven benefits, 2′-FL is now synthesized using microbial fermentation and incorporated into infant formula to closely replicate the composition of human milk. Additionally, it is being explored for its potential applications in dietary supplements and functional foods targeting gut health and immunity.

 

FOCUSFREDA has now launched 2′-Fucosyllactose as our new market ingredient. For more details, please contact sales@focuschem.com.