What ingredient can be applied across skincare, functional foods and medical aesthetics while continuously satisfying diverse consumer demands? It supports skin health by being widely incorporated into daily skincare products including creams, serums and facial masks to enhance hydration and smoothness. It also supports joint health by reducing friction between cartilage surfaces during movement and enabling smoother, more flexible mobility.
This ingredient is sodium hyaluronate, commonly known as hyaluronic acid. As a natural substance found in the human body and hailed as the “natural moisturizing factor”, it is extensively applied in cosmetics, medical aesthetics, pharmaceuticals, nutritional supplements and healthcare products. Located in Jining, Shandong Province, Shandong Focusfreda Biotech Co., Ltd. is a high-tech enterprise specializing in this valuable material. Integrating R&D, production and sales of sodium hyaluronate raw materials and sodium hyaluronate-based end products, the company has established a complete industrial chain from raw materials to finished products.
Pursuing high-value-added development is not only crucial for enterprises to achieve high-quality transformation and growth, but also an indispensable pathway for industries to escape low-end homogeneous competition and enter high-end market segments. Centered on sodium hyaluronate, the company continues to expand application scenarios:
In advanced skincare, continuous technological innovation enables the development of derivatives including acetylated sodium hyaluronate and cross-linked sodium hyaluronate, alongside cellular-level skincare raw materials, supporting the shift from conventional product marketing to technology-driven solution capabilities.
In functional foods, leveraging core raw materials such as medium- and low-molecular-weight sodium hyaluronate and tremella polysaccharides, together with the Group’s proprietary ingredients including gamma-aminobutyric acid (GABA) and plant extracts, Focusfreda develops diversified health food solutions.
In the pharmaceutical and medical device sectors, the company supplies sodium hyaluronate APIs for injection, eye drop excipients and a full portfolio of sodium hyaluronate raw materials required for Class II and Class III medical devices. Boasting a broad molecular weight spectrum, it offers customised production for products below 2.6 million Da to meet the personalised requirements of global clients.
Deep expertise in the sodium hyaluronate sector, breakthroughs in molecular weight limits, and the development of sodium hyaluronate products covering the full molecular weight range from 400 Da to 3.2 million Da form the core strategic pathway for Focusfreda to drive industrial upgrading and high-quality transformation. Iterative upgrading of product technologies relies on sustained breakthroughs in molecular weight control technologies. Taking technological innovation as its core competitiveness, Focusfreda assembles high-calibre R&D teams through cooperation with multiple universities and research institutions, establishing an integrated industry-university-research system linking scientific research and manufacturing.
Through persistent innovation, the company holds a total of 90 valid patents: 5 international invention patents, 26 Chinese invention patents, 56 utility model patents and 3 design patents, building strong technological advantages supported by independent intellectual property rights.
How has Focusfreda repeatedly overcome major technological bottlenecks within the industry? The answer lies in its long-term dedication to R&D innovation and continuous technological accumulation. Thanks to outstanding technical strength and contributions to the industry, Focusfreda has been accredited successively as a National Manufacturing Single Champion Enterprise, National-level Specialized and Innovative “Little Giant” Enterprise, Shandong Gazelle Enterprise and Shandong Technological Innovation Demonstration Enterprise. These accolades consolidate its leading industry position, with products exported to more than 70 countries and regions worldwide.
Beyond breakthroughs in high-molecular-weight products, Focusfreda has developed proprietary advanced plant nitrogen source preparation technology, pushing the industrial fermentation yield of sodium hyaluronate up to 14 g/L. Supported by precision enzymatic degradation technology, the company has realised mass production covering the full molecular weight range of 400 Da to 3.2 million Da, successfully tackling key technological bottlenecks in industrial microbial fermentation.
Powered by these two core technologies, Focusfreda’s products fully meet refined and differentiated application demands across food, beauty, pharmaceutical and other fields. The company is positioned among the global leaders in the sodium hyaluronate raw material market, ranking among the top three worldwide by market share.
